No, the best weapon in the game is itachi's weapon, next is kisame's item. Only this 2 weapon will give effect which other item will not give you. Orochimaru item is quite useless though. Lazy to show out the calculation why it is useless.
Orochimaru can be late gamer as his lv40 skill let him farm alot faster in dragon. but other then that he is useless because his summons can easily countered by increasing armor.